How It Is Given
Getting Started
Most Common
Progesterone therapy
If you still have a uterus, progesterone is not optional. Estrogen on its own thickens the uterine lining over time and raises endometrial cancer risk, and progesterone reverses that. Prescribed for women across Los Angeles.
Why it is added
Progesterone is not there to make estrogen work better; it is there to stop the lining thickening, and that holds for every Los Angeles patient with a uterus. Estrogen stimulates the endometrium to thicken, exactly as it did during your cycle. Without anything to oppose it, that thickening continues and the risk of endometrial hyperplasia and cancer rises with time on treatment.
Progesterone triggers the shedding or stabilising that used to happen naturally each month. Adding it returns endometrial cancer risk to the level of a woman not taking hormone therapy at all.
If you have had a hysterectomy there is no lining to protect and progesterone is not required. Some women take it anyway because of its effect on sleep, and that is a reasonable choice to discuss. Related reading: treatment options, hormone pellets and hormone replacement therapy for the rest of it. Sleep is the exception worth raising: a Los Angeles patient who no longer needs progesterone for protection may still want it for that effect.
Taking it
Micronized progesterone makes most people drowsy within an hour. Taken at bedtime that is a benefit rather than a side effect.
Continuous daily dosing suits most postmenopausal women. Cyclical dosing, twelve to fourteen days a month, suits some women still having periods.
Absorption improves slightly with food, though consistency matters more than timing. Pick one habit and keep it.
Micronized progesterone capsules are suspended in peanut oil. If you have that allergy, say so before anything is prescribed.
Which kind
Two different compounds get discussed under one heading here, and telling them apart matters for anyone in Los Angeles reading older coverage of hormone therapy. Micronized progesterone is the same molecule your body made. Synthetic progestins such as medroxyprogesterone are different compounds that act on the same receptor, and they were what the 2002 WHI trial studied.
That distinction matters when you read about breast cancer risk. Some evidence suggests micronized progesterone carries a lower signal than the synthetic progestins used in the older trials, though the data is not settled enough to promise you a difference. There is more in breast cancer and hrt, about the clinic and non hormonal options go further into it. The honest position in Los Angeles is that the evidence leans toward micronized progesterone without being settled enough to promise you a different outcome.
Related treatments
Progesterone is almost always part of a combination. These are the other components.
The systemic overview: what it treats and how well.
Learn moreThe estrogen most often prescribed, and why a patch usually comes first.
Learn moreLocal treatment for dryness and urinary symptoms.
Learn moreOff-label, unapproved for women, and what the evidence shows.
Learn moreCommon questions
Who needs it, when to take it, and what the sedative effect feels like.
Patient reviews
I had been waking three or four times a night for two years and had been told it was just stress. The consultation actually went through my cycle history. Six weeks on a patch and I am sleeping through.
What I wanted was someone who would talk about the risks honestly rather than sell me something. They walked through the clot data and why a patch suited me better than tablets.
The brain fog was the part nobody warned me about. Having a clinician tell me it was a recognized symptom and not early dementia was worth the appointment on its own.
It took two dose changes before things settled, which they had told me upfront might happen. The three-month review was booked before I left the first appointment.
From the blog
Next step
Whether you still have a uterus, how you sleep, whether you need contraception and any peanut allergy all steer this decision.
Consultations are by appointment. Prescriptions are issued only where clinically appropriate.